LSD1-IN-38
Ref. TM-T204124
Product Information
Name:LSD1-IN-38
Brand:Targetmol
Description:LSD1-IN-38 (Compound 23e) is a reversible, orally active inhibitor of lysine-specific demethylase 1 (LSD1), with an IC50 of 1.2 nM. It effectively inhibits the proliferation of cancer cells MV4-11, Kasumi-1, and NCI-H526 with IC50 values of 5, 4, and 11 nM, respectively. Furthermore, LSD1-IN-38 activates CD86 expression with an EC50 of 0.034 μM and induces differentiation in MV4-11 cells. In mouse models, this compound demonstrates antitumor activity.
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Chemical properties
Molecular weight:535.578
Formula:C30H29F4N5
Color/Form:Solid
Technical inquiry about: LSD1-IN-38
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