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JB300

CAS:

Ref. TM-T204223

JB300
Targetmol

Product Information

Name:JB300
Brand:Targetmol
Description:JB300 is a PROTAC-based compound that serves as a highly selective degrader of Aurora A, with a DC50 of 30 nM. It is utilized in cancer research. JB300 comprises the PROTAC target protein ligand MK-5108 [pink part], E3 ligase ligand Thalidomide-O-COOH [blue part], and PROTAC Linker Boc-NH-PEG2-C2-NH2 [black part]. The conjugate of the E3 ubiquitin ligase ligand and linker is Thalidomide-O-COOH-NH2-C2-PEG2-NH-Boc.
Notice:Our products are intended for lab use only. For any other use, please contact us.

Chemical properties

Molecular weight:906.375
Formula:C43H45ClFN7O10S
Color/Form:Solid

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