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PROTAC AR Degrader-9

Ref. TM-T204370

PROTAC AR Degrader-9
Targetmol

Product Information

Name:PROTAC AR Degrader-9
Brand:Targetmol
Description:PROTAC AR Degrader-9 (Compound c6) is a PROTAC-based degrader specifically targeting the androgen receptor. It effectively degrades the androgen receptor in human dermal papilla cells (HDPC) with a DC50 of 262.38 nM. Additionally, this compound enhances the expression of paracrine factors, such as TGF-β1 and β-catenin, thereby promoting hair regeneration in mouse models. [Pink: ligand for target protein AR ligand-38; Black: linker; Blue: ligand for E3 ligase Cereblon]
Notice:Our products are intended for lab use only. For any other use, please contact us.

Chemical properties

Molecular weight:765.339
Formula:C43H49ClN6O5
Color/Form:Solid

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