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DNA ligase-IN-2

CAS:

Ref. TM-T204415

DNA ligase-IN-2
Targetmol

Product Information

Name:DNA ligase-IN-2
Brand:Targetmol
Description:DNA ligase-IN-2 (compound 2) acts as a potent LigA inhibitor, effectively hindering the DNA-independent spontaneous adenylation activity of full-length LigA and the truncated enzyme LigA:AD with an IC50 of 29 nM. It also significantly suppresses the in vitro growth of Staphylococcus aureus, showing MIC values of 1 μg/mL for S. aureus ATCC 29213 and S. aureus ATCC 700699, while the MIC for Escherichia coli (E. coli) ATCC 25922 is >64 μg/mL.
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Chemical properties

Molecular weight:273.219
Formula:C13H8FN3O3
Color/Form:Solid

Technical inquiry about: DNA ligase-IN-2

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