Product Information
Name:SAL-0010042
Brand:Targetmol
Description:SAL-0010042 is an inhibitor of Plasmodium phosphodiesterase β (PDEβ), effectively blocking the hydrolysis of cAMP and cGMP in gametocytes with an IC50 of 48.9 nM, thereby activating PKG and inhibiting the growth and development of Plasmodium (IC50s for 3D7 and Dd2 are 142 nM and 218 nM, respectively). It also inhibits hPDE5 and hPDE6 with IC50 values of 632 nM and 73 nM, respectively.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:286.304
Formula:C15H15FN4O
Color/Form:Solid
Technical inquiry about: SAL-0010042
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