c-Fos-IN-1
Ref. TM-T204544
Product Information
Name:c-Fos-IN-1
Brand:Targetmol
Description:c-Fos-IN-1 (Compound P16) acts as a c-Jun inhibitor, effectively reducing the mRNA and protein levels of c-Fos. It also inhibits the phosphorylation activity of ERK and the transcriptional activity of AP-1. This compound demonstrates anticancer properties through the inhibition of the ERK/c-Fos/Jun pathway. c-Fos-IN-1 curbs the proliferation and migration of gastric cancer cells, with an IC50 of 2.31 μM for MGC-803 cells, causing cell cycle arrest at the G2/M phase and inducing apoptosis in cancer cells. Additionally, c-Fos-IN-1 hampers the growth of gastric cancer tumors.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:433.582
Formula:C28H35NO3
Color/Form:Solid
Technical inquiry about: c-Fos-IN-1
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