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ER covalent antagonist-1

CAS:

Ref. TM-T204764

ER covalent antagonist-1
Targetmol

Product Information

Name:ER covalent antagonist-1
Brand:Targetmol
Description:ER covalent antagonist-1 (Compound 39D) acts as an antagonist of the estrogen receptor α (ERα). This compound inhibits the proliferation of ERα-positive MCF-7 cells with an IC50 of 0.98 μM, induces cell cycle arrest at the G0/G1 phase, and triggers apoptosis. Additionally, ER covalent antagonist-1 demonstrates antitumor activity in mouse models.
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Chemical properties

Molecular weight:568.683
Formula:C33H32N2O5S
Color/Form:Solid

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