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PROTAC PARP1 degrader-4

Ref. TM-T204787

PROTAC PARP1 degrader-4
Targetmol

Product Information

Name:PROTAC PARP1 degrader-4
Brand:Targetmol
Description:PROTAC PARP1 degrader-4 (Compound 180055) is a selective PARP1 PROTAC degrader, demonstrating DC50 values of 180 nM and 240 nM in T47D and MDA-MB-231 cell lines, respectively. It facilitates the ubiquitination and degradation of PARP1 and inhibits its enzymatic activity without causing significant DNA trapping effects. Additionally, PROTAC PARP1 degrader-4 can inhibit tumors with BRCA gene mutations while having minimal impact on the growth of normal cells.
Notice:Our products are intended for lab use only. For any other use, please contact us.

Chemical properties

Molecular weight:920.145
Formula:C51H62FN7O6S
Color/Form:Solid

Technical inquiry about: PROTAC PARP1 degrader-4

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