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A-800141

CAS:

Ref. TM-T204983

A-800141
Targetmol

Product Information

Name:A-800141
Brand:Targetmol
Description:A-800141 is an orally active and selective MetAP2 inhibitor with an IC50 of 12 nM, while showing weaker inhibitory activity against MetAP1 (IC50: 36 μM). GAPDH can serve as a biomarker for monitoring the inhibition of MetAP2 by A-800141. This compound exhibits anti-angiogenic and anticancer properties in various xenograft tumor models.
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Chemical properties

Molecular weight:442.571
Formula:C24H30N2O4S
Color/Form:Solid

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