Product Information
Name:Pyrimidinone 8
Brand:Targetmol
Description:Pyrimidinone 8 is a reversible, linear non-competitive inhibitor of divalent metal transporter 1 (DMT1) with a Ki of 20 μM (hDMT1). It does not affect the surface expression of hDMT1 and is not influenced by extracellular pH. Pyrimidinone 8 inhibits hDMT1-mediated iron uptake, with an IC50 of 13.8 μM.
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Chemical properties
Molecular weight:204.229
Formula:C10H12N4O
Color/Form:Solid
Technical inquiry about: Pyrimidinone 8
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