Product Information
Name:DP-15
Brand:Targetmol
Description:DP-15 acts as a degrader of GSPT1 and BRD4, with DC50 values of 5.25 nM and 0.48 nM, respectively. This compound exhibits antiproliferative activity in AML and NHL cells, showing IC50 values in the nanomolar range, induces G1 phase cell cycle arrest, and triggers apoptosis in MOLM13 cells. Additionally, DP-15 demonstrates anti-leukemic properties in the MOLM-13 xenograft mouse model. [Pink: ligand for target protein JQ-1 carboxylic acid; Black: linker; Blue: ligand for E3 ligaseCereblonThalidomide-5-OH]
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:822.374
Formula:C42H44ClN9O5S
Color/Form:Solid
Technical inquiry about: DP-15
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