PROTAC ROR1 degrader-1
Ref. TM-T205060
Product Information
Name:PROTAC ROR1 degrader-1
Brand:Targetmol
Description:PROTACROR1degrader-1 (Compound 11d) serves as a PROTAC degrader targeting the pseudokinase ROR1, with the capability of degrading ROR1 in NSCLC cells at a DC50 of 40-80 nM. It induces PARP cleavage and apoptosis in NCI-H23 cells. [Pink: ligand for target protein ROR1 ligand-1; Black: linker; Blue: ligand for VHL E3 ligase (S,R,S)-AHPC]
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:1081.22
Formula:C55H74BrN11O5S
Color/Form:Solid
Technical inquiry about: PROTAC ROR1 degrader-1
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