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ERK1/2 inhibitor 13

Ref. TM-T205076

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Targetmol

Product Information

Name:ERK1/2 inhibitor 13
Brand:Targetmol
Description:ERK1/2 inhibitor 13 (Compound 21y) is an orally bioavailable ERK inhibitor that targets ERK1 and ERK2, with IC50 values of 91.71 nM and 97.87 nM, respectively. It effectively suppresses the proliferation of cancer cell lines MCF-7, 4T1, MDA-MB-468, and HCC1970 with IC50 values of 0.67 μM, 2.76 μM, 2.15 μM, and 1.68 μM, respectively. Additionally, it inhibits cancer cell migration, induces apoptosis and autophagy in MCF-7 cells, and demonstrates anti-tumor and anti-metastatic effects in a 4T1 xenograft mouse model.
Notice:Our products are intended for lab use only. For any other use, please contact us.

Chemical properties

Molecular weight:727.54
Formula:C36H29BrF6N4O
Color/Form:Solid

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