(E)-2,6-Di-tertbutyl-4(4-(diethylamino)styryl)pyrylium TFA
CAS:
Ref. TM-T205077
10mg
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50mg
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Product Information
Name:(E)-2,6-Di-tertbutyl-4(4-(diethylamino)styryl)pyrylium TFA
Brand:Targetmol
Description:(E)-2,6-Di-tert-butyl-4-(4-(diethylamino)styryl)pyrylium TFA (Compound 4a) functions as a Gram-negative outer membrane permeabilizer by targeting Met47 in LptA to disrupt LptA/LptC interactions, exhibiting synergistic antibacterial activity. This compound, when in the form of (trifluoromethanesulfonate), enhances the efficacy of pol B against both wild-type and multi-drug resistant A. baumannii and E. coli strains. Additionally, (E)-2,6-Di-tert-butyl-4-(4-(diethylamino)styryl)pyrylium (trifluoromethanesulfonate) serves as an adjuvant for antibiotics combating multi-drug resistant Gram-negative bacteria.
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Chemical properties
Molecular weight:515.629
Formula:C26H36F3NO4S
Color/Form:Solid
Technical inquiry about: (E)-2,6-Di-tertbutyl-4(4-(diethylamino)styryl)pyrylium TFA
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