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Quorum sensing-IN-9

CAS:

Ref. TM-T205120

Quorum sensing-IN-9
Targetmol

Product Information

Name:Quorum sensing-IN-9
Brand:Targetmol
Description:Quorum sensing-IN-9 (Compound 7d) inhibits quorum sensing in Pseudomonas aeruginosa by binding to the PqsR protein. It suppresses the expression of quorum sensing system-related genes lasB, rhlA, and pqsA, thereby preventing the production of virulence factors elastase, pyocyanin, and rhamnolipid. Quorum sensing-IN-9 disrupts the motility of P. aeruginosa, inhibits biofilm formation, and reduces the bacterium's virulence and pathogenicity. Additionally, it exhibits anti-infective activity in the Galleria mellonella larval model.
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Chemical properties

Molecular weight:198.305
Formula:C9H10OS2
Color/Form:Solid

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