SHP2-IN-35
Ref. TM-T205173
Product Information
Name:SHP2-IN-35
Brand:Targetmol
Description:SHP2-IN-35 (Compound 3f) functions as an inhibitor of SHP2. It exhibits antiproliferative activity in cancer cell lines RKO, SW480, and CT26, with IC50 values of 5.72 μM, 3.71 μM, and 1.42 μM, respectively. SHP2-IN-35 inhibits the PI3K-Akt signaling pathway, regulates the expression of cell cycle-related genes, and induces mitochondrial autophagy (autophagy). Within the tumor microenvironment (TME), SHP2-IN-35 suppresses the expression of certain cytokines and chemokines, thereby modulating tumor progression.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:592.46
Formula:C34H32FeO6
Color/Form:Solid
Technical inquiry about: SHP2-IN-35
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