Tubulin polymerization-IN-76
Ref. TM-T205237
Product Information
Name:Tubulin polymerization-IN-76
Brand:Targetmol
Description:Tubulin polymerization-IN-76 (compound 20b) is a potent and orally active inhibitor of tubulin polymerization. It acts at the colchicine binding site to inhibit tubulin polymerization with an IC50 value of 2.505 μM, effectively disrupting the intracellular microtubule network and interfering with mitosis. Tubulin polymerization-IN-76 shows significant inhibitory effects on MGC-803 and HGC-27 cells, with IC50 values of 1.61 and 1.82 nM, respectively. It effectively suppresses colony formation and cell migration activities in these cell lines, inducing G2/M phase cell cycle arrest and apoptosis (Apoptosis). Furthermore, Tubulin polymerization-IN-76 exhibits broad-spectrum antiproliferative activity.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:363.48
Formula:C20H21N5S
Color/Form:Solid
Technical inquiry about: Tubulin polymerization-IN-76
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