Antitumor agent-195
Ref. TM-T205391
Product Information
Name:Antitumor agent-195
Brand:Targetmol
Description:Antitumor agent-195 (compound 16c) is a dual-targeting agent that simultaneously targets STAT3 and NQO1. At a concentration of 1 μM, it significantly inhibits the phosphorylation of STAT3 at the Tyr705 site and effectively induces apoptosis in MDA-MB-231 and MDA-MB-468 breast cancer cells. As a substrate of NQO1, Antitumor agent-195 markedly increases ROS production, causing severe DNA damage in a dose-dependent manner. It also demonstrates strong antitumor properties in MDA-MB-231 xenograft models.
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Chemical properties
Molecular weight:378.42
Formula:C22H22N2O4
Color/Form:Solid
Technical inquiry about: Antitumor agent-195
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