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BRD4 Inhibitor-40

CAS:

Ref. TM-T205510

BRD4 Inhibitor-40
Targetmol

Product Information

Name:BRD4 Inhibitor-40
Brand:Targetmol
Description:BRD4 Inhibitor-40 (Compound 23) functions as an inhibitor of BRD, effectively targeting BRD4-BD1, BRD4-BD2, BRD2-BD1, and BRD2-BD2, with IC50 values of 16.1, 142.18, 29.35, and 302.35 nM, respectively. It modulates the expression of c-Myc and p21, induces cell cycle arrest in the G1 phase, and inhibits Pkd1-deficient (PN) renal cystic epithelial cells. Additionally, it prevents renal cyst formation in both Madin-Darby canine kidney and embryonic kidney cyst models, and demonstrates renal cyst inhibition activity in mouse models.
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Chemical properties

Molecular weight:484.596
Formula:C27H32N8O
Color/Form:Solid

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