Topo I/II-IN-2
Ref. TM-T205531
Product Information
Name:Topo I/II-IN-2
Brand:Targetmol
Description:Topo I/II-IN-2 (Compound 3g) is an inhibitor of both Topo I and Topo II. It exhibits inhibitory activity against NCI-H446 and NCI-H1048 cells with IC50 values of 1.30 μM and 1.42 μM, respectively. Topo I/II-IN-2 induces mitochondrial apoptosis, disrupts mitochondrial function, and stimulates activity generation. Additionally, it inhibits the PI3K/Akt/mTOR pathway, effectively preventing the proliferation, invasion, and migration of small cell lung cancer (SCLC) cells in vitro.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:418.48
Formula:C25H26N2O4
Color/Form:Solid
Technical inquiry about: Topo I/II-IN-2
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