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BRD6257

Ref. TM-T205561

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Targetmol

Product Information

Name:BRD6257
Brand:Targetmol
Description:BRD6257 is an orally active inhibitor of protein phosphatase 1D (proteinphosphatase, Mg2+/Mn2+ dependent 1D, PPM1D) with an IC50 of 5 nM. It activates the p53 signaling pathway (EC50 of 51 nM), enhances p21 expression, and inhibits the proliferation of cancer cells MOLM13 (IC50 = 2.8 μM). BRD6257 demonstrates good metabolic stability in human and rat liver microsomes.
Notice:Our products are intended for lab use only. For any other use, please contact us.

Chemical properties

Molecular weight:550.53
Formula:C24H22F4N6O3S
Color/Form:Solid

Technical inquiry about: BRD6257

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