
BKCa activator-1
Ref. TM-T205564

Product Information
Name:BKCa activator-1
Brand:Targetmol
Description:BKCa activator-1 (Compound 51b) is an orally active activator of BKCa calcium-activated potassium channels with an EC50 of 2.82 μM. It promotes K+ efflux, leading to cell membrane hyperpolarization and inhibition of smooth muscle contraction. In a spontaneous hypertensive rat (SHR) model, it alleviates urinary incontinence and exhibits antitussive effects in a guinea pig cough model.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:496.418
Formula:C22H23F7N2O3
Color/Form:Solid
Technical inquiry about: BKCa activator-1
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