Product Information
Name:P162-0948
Brand:Targetmol
Description:P162-0948 is a selective CDK8 inhibitor with an IC50 value of 50.4 nM. It reduces cell migration and the expression of EMT-related proteins in the A549 human alveolar epithelial cell line. Furthermore, P162-0948 decreases Smad phosphorylation, indicating disruption of the TGF-β/Smad signaling pathway, making it a promising compound for pulmonary fibrosis research.
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Chemical properties
Molecular weight:362.357
Formula:C20H15FN4O2
Color/Form:Solid
Technical inquiry about: P162-0948
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