AA-BR-157
Ref. TM-T205636
Product Information
Name:AA-BR-157
Brand:Targetmol
Description:AA-BR-157 is a PROTAC degrader targeting metallothionein 2A (MT2A) with a DC50 of 190 nM. It downregulates DIAPH3, a protein involved in cytoskeletal and cellular movement regulation, inhibiting cell migration in MDA-MB-231 and U-87 MG cell lines. Additionally, AA-BR-157 modulates zinc homeostasis in MDA-MB-231 cells. (Pink: ligand for target protein MT2A ligand 1; Black: linker; Blue: ligand for VHL E3 ligase).
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:1095.33
Formula:C56H70N8O11S2
Color/Form:Solid
Technical inquiry about: AA-BR-157
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