PROTAC cGAS degrader-1
Ref. TM-T205651
Product Information
Name:PROTAC cGAS degrader-1
Brand:Targetmol
Description:PROTAC cGAS degrader-1 (Compound TH35) is a potent and selective cGAS PROTAC degrader, exhibiting DC50 values of 0.9 μM in THP-1 cells and 4.6 μM in RAW 264.7 cells. It effectively inhibits the activation of cGAS signaling induced by dsDNA. PROTAC cGAS degrader-1 also demonstrates anti-inflammatory properties, making it suitable for research into cGAS-related inflammatory diseases. (Pink: cGAS inhibitor; Black: Linker; Blue: E3 ligase ligand)
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:714.6
Formula:C36H33Cl2N7O5
Color/Form:Solid
Technical inquiry about: PROTAC cGAS degrader-1
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