Autophagy agonist-1
Ref. TM-T205669
Product Information
Name:Autophagy agonist-1
Brand:Targetmol
Description:Autophagyagonist-1 (compound 22) is an autophagy agonist. It exhibits significant anticancer activity against HepG2 cells and normal cells, with IC50 values of 8.8 μM and > 50 μM, respectively. The compound induces G1/S phase cell cycle arrest, suppresses the expression of CDK4 and CyclinD1, and upregulates P21. Additionally, Autophagyagonist-1 enhances autophagosome, LC3, and PINK1 accumulation, thereby promoting autophagy and mitophagy in HepG2 cells.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:559.7
Formula:C33H41N3O5
Color/Form:Solid
Technical inquiry about: Autophagy agonist-1
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