Product Information
Name:NU227326
Brand:Targetmol
Description:NU227326 is a PROTAC degrader of indoleamine 2,3-dioxygenase 1 (IDO1) with a DC50 value of 4.5 nM. It effectively degrades IDO1 in U87 and GBM43 cells, with DC50 values of 7.1 nM and 11.8 nM, respectively. NU227326 exhibits favorable pharmacokinetic properties, with a plasma half-life of 5.7 hours and a brain tissue half-life of 11.8 hours. (Pink: ligand for target protein IDO1 ligand-1; Black: linker; Blue: ligand for E3 ligase Cereblon).
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:941.099
Formula:C53H61FN8O7
Color/Form:Solid
Technical inquiry about: NU227326
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