FTO-IN-14
Ref. TM-T205742
10mg
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50mg
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Product Information
Name:FTO-IN-14
Brand:Targetmol
Description:FTO-IN-14 (Compound F97) is an inhibitor of the RNA demethylase Fat mass and obesity-associated protein (FTO), with an IC50 of 0.45 μM. It modulates the expression of the ASB2, RARA, and MYC proteins. FTO-IN-14 demonstrates antiproliferative activity in AML cancer cells, with IC50 values of 0.7-5.5 μM against MOLM13, NB4, HEL, OCI-AML3, MV4-11, and MONOMAC6, and induces apoptosis in NB4 cells. Additionally, FTO-IN-14 exhibits antitumor activity in a mouse NB4 xenograft model.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:393.502
Formula:C22H23N3O2S
Color/Form:Solid
Technical inquiry about: FTO-IN-14
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