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HDAC-IN-27 dihydrochloride

CAS:

Ref. TM-T206628

HDAC-IN-27 dihydrochloride
Targetmol

Product Information

Name:HDAC-IN-27 dihydrochloride
Brand:Targetmol
Description:HDAC-IN-27 dihydrochloride (Compound 11h) is a potent, orally active, HDACI class-selective inhibitor, with IC50 values ranging from 0.43 to 3.01 nM for HDAC1-3. This compound exhibits both in vivo and in vitro anticancer activity. HDAC-IN-27 shows significant antiproliferative effects against acute myeloid leukemia (AML) cell lines by inducing apoptosis and histone acetylation (AcHH3 and AcHH4). It is useful for research on acute myeloid leukemia (AML).
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Chemical properties

Molecular weight:423.336
Formula:C20H24Cl2N4O2
Color/Form:Solid

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