Product Information
Name:ASTX295
Brand:Targetmol
Description:ASTX295 is a selective mouse double minute 2 (MDM2) antagonist with an IC50 value of less than 1 nM. It specifically inhibits the interaction between MDM2 and p53, reactivating wild-type (WT) TP53, which subsequently induces the expression of related transcriptional targets, leading to cell death and cell cycle arrest. ASTX295 holds potential for research in lymphoid malignancies such as diffuse large B-cell lymphoma (DLBCL), mantle cell lymphoma (MCL), and T-cell lymphoma.
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Chemical properties
Molecular weight:630.531
Formula:C33H34Cl2FNO6
Color/Form:Solid
Technical inquiry about: ASTX295
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