Product Information
Name:2-Guanidinobezimidazole
Synonyms:
- 2GBI
Brand:Targetmol
Description:2-Guanidinobenzimidazole (2GBI) is a selective agonist of NLRP3, with a KD value of 1.29 μM for His-GFP-NLRP3. It directly binds to the LRR domain of NLRP3, facilitating the assembly and activation of the inflammasome. Additionally, 2-Guanidinobenzimidazole enhances antitumor immunity, inhibits tumor growth, and overcomes resistance to immune checkpoint blockade (ICB).
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Chemical properties
Molecular weight:175.191
Formula:C8H9N5
Color/Form:Solid
Technical inquiry about: 2-Guanidinobezimidazole
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