hSTING activator-1
Ref. TM-T206918
Product Information
Name:hSTING activator-1
Brand:Targetmol
Description:hSTING activator-1 (Compound 68) is a STING agonist capable of effectively activating various human STING variants (R232, H232, HAQ), with EC50 values of 56 nM, 89 nM, and 51 nM, respectively. This compound activates the type I interferon pathway by directly binding to the STING protein and stabilizing its conformation, which leads to downstream IRF3 phosphorylation and cytokine release. hSTING activator-1 also demonstrates potential in cancer research by inhibiting fibrosarcoma tumor growth.
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Chemical properties
Color/Form:Odour Solid
Technical inquiry about: hSTING activator-1
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