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(S)-dHTC1

CAS:

Ref. TM-T206969

(S)-dHTC1
Targetmol

Product Information

Name:(S)-dHTC1
Brand:Targetmol
Description:(S)-dHTC1 is a molecular glue degrader specifically targeting the transcriptional coactivator ENL. It exhibits high affinity binding to E3 ligase only upon formation of the ENL:(S)-dHTC1 complex, with an IC50 of 93 nM. In MV4;11 cells, (S)-dHTC1 degrades ENL with a DC50 of 26 nM. This compound can be utilized for acute myeloid leukemia research.
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Chemical properties

Molecular weight:676.786
Formula:C33H40N8O6S
Color/Form:Solid

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