PROTAC MNK1 degrader-1
Ref. TM-T207111
Product Information
Name:PROTAC MNK1 degrader-1
Brand:Targetmol
Description:ROTACMNK1degrader-1 is a selective MNK1 PROTAC degrader with a DC50 of 11.92 nM and a Dmax greater than 96% in MV4-11 cells. It significantly reduces p-eIF4E levels with an IC50 of 22.07 nM, induces apoptosis, and causes cell cycle arrest at the G1 phase. This compound exhibits potent antitumor activity, demonstrating strong anti-leukemic effects in MV4-11 xenograft mouse models with acceptable drug safety.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:670.78
Formula:C35H38N6O6S
Color/Form:Solid
Technical inquiry about: PROTAC MNK1 degrader-1
Please use instead the cart to request a quotation or an order
If you want to request a quotation or place an order, please instead add the desired products to your cart and then request a quotation or order from the cart. It is faster, cheaper, and you will be able to benefit from the available discounts and other advantages.