IDO1/TDO-IN-8
Ref. TM-T207127
Product Information
Name:IDO1/TDO-IN-8
Brand:Targetmol
Description:IDO1/TDO-IN-8 (Compound CZ-17) is a dual IDO1 and TDO inhibitor capable of crossing the blood-brain barrier, with EC50 values of 0.33 μM and 1.78 μM, respectively. It modulates the kynurenine pathway of tryptophan metabolism, reducing the kynurenine/tryptophan ratio. IDO1/TDO-IN-8 has neuroprotective effects, alleviating motor dysfunction and improving depressive behavior, making it relevant for research into Parkinson's disease with comorbid depression.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:278.37
Formula:C17H14N2S
Color/Form:Solid
Technical inquiry about: IDO1/TDO-IN-8
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