CHK1-IN-12
Ref. TM-T207228
Product Information
Name:CHK1-IN-12
Brand:Targetmol
Description:CHK1-IN-12 (Compound example 1-5) is a highly selective and orally active checkpoint kinase 1 (CHK1) inhibitor, demonstrating an in vitro enzyme IC50 of ≤10 nM and a cellular IC50 of ≤50 nM. This compound suppresses the phosphorylation activity of CHK1 kinase, disrupts DNA damage response pathways, and induces tumor cell cycle arrest and apoptosis. CHK1-IN-12 shows promise for cancer research applications.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:377.16002
Formula:C19H19N7O2
Color/Form:Solid
Technical inquiry about: CHK1-IN-12
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