VEN-02XX
Ref. TM-T207260
Product Information
Name:VEN-02XX
Brand:Targetmol
Description:VEN-02XX is an orally active NLRP3 inhibitor capable of penetrating the brain. It effectively suppresses the release of IL-1β and IL-18, with IC50 values of 0.3 and 0.28 μM, respectively. In the 5XFAD/Rubicon KO mouse model, VEN-02XX aids in restoring memory and cognition, inhibits microgliosis, and alleviates neuroinflammation and tau protein pathology. This compound is valuable for Alzheimer's disease (AD) research.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:396.79
Formula:C18H16ClF3N4O
Color/Form:Solid
Technical inquiry about: VEN-02XX
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