CDK9 degrader-1
Ref. TM-T207627
Product Information
Name:CDK9 degrader-1
Brand:Targetmol
Description:CDK9degrader-1 is a selective CDK9 degrader (DC50: 0.4073 µM). It recruits ATG101 to initiate the autophagy-lysosome pathway and forms autophagosomes by recruiting LC3, which then fuse with lysosomes to degrade CDK9 and its partner protein, Cyclin T1 (DC50: 1.215 µM). CDK9degrader-1 induces caspase 3-mediated apoptosis and exhibits antitumor activity in a mouse HCT116 xenograft model.
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Chemical properties
Molecular weight:637.56
Formula:C32H34Cl2N6O4
Color/Form:Solid
Technical inquiry about: CDK9 degrader-1
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