MS2133
Ref. TM-T207647
Product Information
Name:MS2133
Brand:Targetmol
Description:MS2133 is a DOT1L PROTAC degrader. It facilitates the ubiquitination and degradation of DOT1L in THP-1 and MV4-11 cells, with DC50 values of 56 nM and 25 nM, respectively, and reduces H3K79 methylation. MS2133 also inhibits the growth of MLL-r leukemia cells, demonstrating anticancer activity.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:1290.41175
Formula:C58H66ClF3N14O11S2
Color/Form:Solid
Technical inquiry about: MS2133
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