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HDSI-18

Ref. TM-T207650

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Targetmol

Product Information

Name:HDSI-18
Brand:Targetmol
Description:HDSI-18 is an orally active selective inhibitor of HDAC6 with an IC50 of 1.6 nM. It exhibits cytotoxic effects against K562, MV4-11, MOLM-13, THP-1, and Jurkat cells with IC50 values of 0.48, 0.58, 0.91, 1.79, and 4.31 μM, respectively. HDSI-18 can activate Caspase-3, induce mitochondrial depolarization, and trigger apoptosis (Apoptosis), demonstrating antitumor activity.
Notice:Our products are intended for lab use only. For any other use, please contact us.

Chemical properties

Molecular weight:500.20597
Formula:C28H28N4O5
Color/Form:Solid

Technical inquiry about: HDSI-18

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