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HQY1428

Ref. TM-T207664

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Targetmol

Product Information

Name:HQY1428
Brand:Targetmol
Description:HQY1428 is an orally active CDK12 inhibitor. It impedes DNA replication, causing cell cycle arrest at the G2/M phase in SKOV3 cells, and induces DNA double-strand breaks as well as apoptosis. In the SKOV3 xenograft mouse model, HQY1428 demonstrates antitumor activity. Additionally, when combined with the HER2 inhibitor Lapatinib in the NCI-N87 xenograft mouse model, HQY1428 produces a synergistic therapeutic effect.
Notice:Our products are intended for lab use only. For any other use, please contact us.

Chemical properties

Molecular weight:546.16162
Formula:C25H28ClFN6O3S
Color/Form:Solid

Technical inquiry about: HQY1428

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