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PLD1 Inhibitor

CAS:

Ref. TM-T207752

10mg
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50mg
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PLD1 Inhibitor
Targetmol

Product Information

Name:PLD1 Inhibitor
Synonyms:
  • Phospholipase D1 Inhibitor
Brand:Targetmol
Description:PLD1 inhibitor is a compound that targets phospholipase D1 (PLD1). It suppresses PLD activity in A549 cells overexpressing PLD1 with an IC50 of 1.97 µM. This inhibitor also decreases the viability of A549 lung cancer and HCT116 colorectal cancer cells, with IC50 values of 18 and 29 µM, respectively. Furthermore, it impairs proliferation, migration, and invasion of A549 cells and triggers apoptosis. Administered at 10 mg/kg every other day, PLD1 inhibitor diminishes tumor growth, induces intratumoral apoptosis, and lowers levels of Ras, CD47, CD24, and programmed cell death 1 ligand 1 (PD-L1) in a murine Lewis lung carcinoma model.
Notice:Our products are intended for lab use only. For any other use, please contact us.

Chemical properties

Molecular weight:400.32
Formula:C19H14F6N2O
Color/Form:Solid

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