PARP/EZH2-IN-2
Ref. TM-T208807
Product Information
Name:PARP/EZH2-IN-2
Brand:Targetmol
Description:PARP/EZH2-IN-2 (compound 12e) functions as a dual inhibitor targeting both PARP1 and EZH2, with IC50 values of 6.89 and 27.34 nM, respectively. This compound exhibits anticancer activity without toxicity to normal cells, achieving synthetic lethality indirectly by increasing PARP1 sensitivity through EZH2 inhibition, and inducing cell death by modulating excessive autophagy.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:573.24884
Formula:C33H31N7O3
Technical inquiry about: PARP/EZH2-IN-2
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