PROTAC GPX4 degrader-2
Ref. TM-T209085
Product Information
Name:PROTAC GPX4 degrader-2
Brand:Targetmol
Description:PROTACGPX4 degrader-2 (compound 18a) is a proteolysis-targeting chimera (PROTAC) that targets the degradation of glutathione peroxidase 4 (GPX4), with a DC50, 48h value of 1.68 μM. It induces the accumulation of lipid peroxides and mitochondrial depolarization, subsequently triggering ferroptosis. Additionally, PROTACGPX4 degrader-2 exhibits antiproliferative activity.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:952.425
Formula:C50H61ClN8O9
Technical inquiry about: PROTAC GPX4 degrader-2
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