KDM5B-IN-4
Ref. TM-T209524
10mg
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50mg
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Product Information
Name:KDM5B-IN-4
Brand:Targetmol
Description:KDM5B-IN-4 (compound 11ad) is a novel inhibitor of lysine demethylase 5B (KDM5B), with an IC50 of 0.025 μM for KDM5B. It increases the levels of the substrate H3K4me1/2/3 in PC-3 cells by inhibiting KDM5B. Furthermore, KDM5B-IN-4 induces G2/M phase arrest in PC-3 cells and downregulates proteins in the PI3K/AKT signaling pathway. Additionally, KDM5B-IN-4 reduces tumor volume in mice with minimal organ toxicity.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:490.24811
Formula:C30H30N6O
Technical inquiry about: KDM5B-IN-4
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