Ru-Poma
Ref. TM-T209925
Product Information
Name:Ru-Poma
Brand:Targetmol
Description:Ru-Poma is an Ru(II)-based photosensitizer designed to enhance the efficacy of photodynamic therapy (PDT) against tumors resistant to Cisplatin. It targets Pomalidomide to partially degrade CRBN, inducing ferroptosis by increasing lipid peroxides and downregulating GPX4 and GAPDH expression. In A549 cells, Ru-Poma exhibits cytotoxicity with IC50 values of 18.46 μM in the dark and 0.37 μM under illumination.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Formula:C89H75Cl2N11O11Ru·7H2O
Technical inquiry about: Ru-Poma
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