Product Information
Name:Hdm2 E3 ligase inhibitor 1
Brand:Targetmol
Description:Hdm2 E3ligaseinhibitor 1 (Compound 1) is a reversible inhibitor of Hdm2-mediated p53 protein ubiquitination, with an IC50 of 12.7 μM. It binds to Hdm2, blocking the transfer of ubiquitin catalyzed by Hdm2 from pre-linked Ub-Ubc4 to p53, thereby inhibiting p53 ubiquitination, stabilizing p53 protein in tumor cells, and exerting antitumor activity.
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Chemical properties
Molecular weight:350.24
Formula:C10H8F6N2O3S
Technical inquiry about: Hdm2 E3 ligase inhibitor 1
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