SL44
Ref. TM-T210251
Product Information
Name:SL44
Brand:Targetmol
Description:SL44 is an agonist of human caseinolytic protease P (HsClpP) with an EC50 of 1.30 μM. It inhibits LM3 proliferation with an IC50 of 3.1 μM and induces apoptosis in liver cancer cells by degrading respiratory chain complex subunits. In mouse models, SL44 demonstrates antitumor activity without significant toxicity (LD50=400 mg/kg) and exhibits favorable pharmacokinetic properties in rat models.
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Chemical properties
Molecular weight:410.13097
Formula:C22H20ClFN4O
Technical inquiry about: SL44
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