HL435
Ref. TM-T210387
10mg
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50mg
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Product Information
Name:HL435
Brand:Targetmol
Description:HL435 is a heterobifunctional molecule that degrades BRD4 by linking with JQ1, with DC50 values of 11.9 nM and 21.9 nM in MDA-MB-231 and MCF-7 cells, respectively. It inhibits the proliferation of MDA-MB-231, MCF-7, 22Rv1, and A549 cells, arrests the cell cycle, and induces apoptosis. Additionally, HL435 exhibits antitumor activity in mouse models.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:1025.21599
Formula:C47H48BrClF3N7O7S
Technical inquiry about: HL435
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