Product Information
Name:HTS05585
Brand:Targetmol
Description:HTS05585 (Compound Hit-1) is a selective inhibitor of macrophage migration inhibitory factor (MIF) with a Kd value of 0.29 μM determined by microscale thermophoresis (MST) and confirmed through isothermal titration calorimetry (ITC) at 0.32 μM. It suppresses the release of pro-inflammatory factors (TNF-α, IL-6, IL-1β) in macrophages induced by LPS, making it a promising candidate for the study of inflammatory diseases such as sepsis.
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Chemical properties
Molecular weight:289.33
Formula:C18H15N3O
Color/Form:Solid
Technical inquiry about: HTS05585
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